Faculty Guide

Title

Victor and Gwendolyn Beinfield Professor of Neuroscience

Biology
Health: Science, Society, and Policy
Volen National Center for Complex Systems

Expertise

Neurotransmitter modulation of neural circuits.

Awards and Honors

George A. Miller Prize, Cognitive Neuroscience Society (2012)

Karl Spenser Lashley Prize, American Philosophical Society (2012)

Honorary Doctor of Science, Bowdoin College (2010)

Fellow, Biophysical Society (2008)

Past President, Society for Neuroscience (2008)

Member, National Academy of Sciences (2007)

President, Society for Neuroscience (2007 - 2008)

Gerard Prize, Society for Neuroscience (2005)

Trustee of the Grass Foundation (2002 - 2005)

Women in Neuroscience Mika Salpeter Lifetime Achievement Award (2002 - 2003)

Fellow, American Academy of Arts and Sciences (2001)

Forbes Lecturer, MBL (2001)

MERIT (Method to Extend Rewearch in Time) Award, National Institutes of Health (1995 - 2000)

McKnight Endowment fund for Neuroscience Investigator Award (1994)

Victor and Gwendolyn Beinfield Chair (1994)

Fellow, American Association for the Advancement of Science (1992 - 1993)

Jacob Javits Neuroscience Investigator Award, National Advisory Neurological and Communicative Disorders and Stroke Council (1987 - 1994)

Sloan Foundation Fellowship (1980)

Courses Taught

BIOL	149b	Molecular Pharmacology
CONT	300b	Responsible Conduct of Science
NBIO	140b	Principles of Neuroscience

Scholarship

Gutierrez, G.J., O’Leary, T., and Marder, E.. "Multiple Mechanisms Switch an Electrically Coupled, Synaptically Inhibited Neuron Between Competing Oscillator Networks.." Neuron 77. (2013): 845-858.

Marder, E.. "Crossing oceans. eLife 2013;2:e00477.." eLife 2. (2013): e00477..

Rinberg, A., Taylor, A.L., and Marder, E.. "The effects of temperature on the stability of a neuronal oscillator.." PLoS Comput Biol 9. 1 (2013): e1002857..

Brookings, T., Grashow, R. and Marder, E.. "Statistics of neuronal identification with open and closed loop measures of intrinsic excitability.." Front. Neural Circuits 6. (2012): 6:19..

Callaway, E.M. and Marder, E.. "Common Features of Diverse Circuits.." Current Opinion in Neurobiology 22. (2012): 565-567..

Kispersky, T., Caplan, J., and Marder, E. ". Increase in sodium conductance decreases firing rate and gain in model neurons.." J. Neurosci 32. (2012): 10995– 10995..

Marder, E. "A good life.." eLIfe 1. (2012): e00353.

Marder, E. "Neuromodulation of neuronal circuits: back to the future.." Neuron 76. (2012): 1-11.

Tang, L.S., Taylor, A.L., Rinberg, A., and Marder, E.. "Robustness of a rhythmic circuit to short and long-term temperature changes.." J. Neurosci. 32. (2012): 10075-10085..

Kispersky, T., Gutierrez, G., and Marder, E.. "Functional connectivity in a rhythmic inhibitory circuit using Granger causality." Neural Systems & Circuits 1:9. (2011): 9.

Marder, E. (2011). "Variability, compensation, and modulation in neurons and circuits." PNAS 108. (2011): 15542-15548.

Marder, E., Taylor, A. L.. "Multiple models to capture the variability in biological neurons and networks." Nat Neurosci 14. 2 (2011): 133-8.

Szabo, T.M., Chen, R., Goeritz, M., Maloney, R.T., Tang, L.S., Li, L., and Marder, E.. "Distribution and physiological effects of B-type allatostatins in the stomatogastric nervous system of the crab, Cancer borealis." J. Comp. Neurol 519. (2011): 2658-2676.

Goaillard, J. M., Taylor, A. L., Pulver, S. R., Marder, E.. "Slow and persistent postinhibitory rebound acts as an intrinsic short-term memory mechanism." J Neurosci 30. 13 (2010): 4687-92.

Goaillard, J.-M, Taylor, A.L., Pulver, S.R. and Marder, E. (2010). "Slow and persistent postinhibitory rebound acts as an intrinsic short-term memory mechanism.." J. Neuroscience 30. (2010): 4687-4692.

Grashow, R., Brookings, T., Marder, E.. "Compensation for variable intrinsic neuronal excitability by circuit-synaptic interactions." J Neurosci 30. 27 (2010): 9145-56.

Marder, E., Kettenmann, H., Grillner, S.. "Impacting our young." Proc Natl Acad Sci U S A (2010).

Marder, E., Tang, L. S.. "Coordinating different homeostatic processes." Neuron 66. 2 (2010): 161-3.

Marder, E.. "Why so long?." Curr Biol 20. 10 (2010): R426.

Tang, L. S., Goeritz, M. L., Caplan, J. S., Taylor, A. L., Fisek, M., Marder, E.. "Precise temperature compensation of phase in a rhythmic motor pattern." PLoS Biol 8. 8 (2010).

Goaillard, J.-M., Taylor, A.L., Schulz, D., and Marder, E.. "Multi-dimensional measurements to understand the functional consequences of animal-to-animal variation in circuit parameters.." Nature Neuroscience, 12. (2009): 1424-1430.

Grashow, R., Brookings, T. and Marder, E.. "Reliable neuromodulation from circuits with variable underlying structure.." Proc Natl Acad Sci USA 106. (2009): 11742-11746.

Ma, M, Szabo, T., Jia, C., Marder, E. and Li, L.. "Mass spectrometric characterization and physiological action of novel crustacean C-type allatostatins.." Peptides 30. (2009): 1660-1668.

Marder, E. "Electrical synapses: rectification demystified.." Curr. Biol. 19. (2009): R34-R35.

Taylor, A.L., Goaillard, J-M, and Marder, E. "How multiple conductances determine electrophysiological properties in a multicompartmental model.." J Neuroscience 29. (2009): 29: 5573-5586.

Tobin A-E, Cruz-Bermúdez ND, Marder E, Schulz DJ (2009). "Correlations in Ion Channel mRNA in Rhythmically Active Neurons.." PLoS ONE 4. 8 (2009): e6742..

Tobin, A.-E., Tang, L.S., Grashow, R.G., Pulver, S.R., and Marder, E.. "Using the dynamic clamp to explore the relationship between intrinsic activity and network dynamics." Dynamic Clamp.. Ed. Destexhe, A., Bal, T. eds.. Springer Series in Computational Neuroscience, 2009

Cape, S.S., Rehm, K.J., Ma, M., Marder, E., and Li, L.. "Mass Spectral Comparison of the Neuropeptide Complement of the Stomatogastric Ganglion and Brain in the Adult and Embryonic Lobster, Homarus americanus.." J Neurochem 105. (2008): 690-702.

Marder, E. "The roads not taken.." Current Biol. 18. (2008): R725- R726..

Rehm, K.R., Deeg, K. and Marder, E.. "Developmental regulation of neuromodulator function in the stomatogastric ganglion of the lobster, Homarus americanus.." J. Neuroscience 28. (2008): 9828-9839.

Rehm, K.R., Taylor, A.L., Pulver, S.R. and Marder, E. "Spectral analyses reveal the presence of adult-like activity in the embryonic stomatogastric motor patterns of the lobster, Homarus americanus.." J Neurophysiol 99. (2008): 3104-3122.

Bucher, D., Johnson, C. D., Marder, E. "Neuronal morphology and neuropil structure in the stomatogastric ganglion of the lobster, Homarus americanus." J Comp Neurol 501. 2 (2007): 185-205.

Cruz-Bermúdez, N. and Marder, E. "Multiple modulators act on the cardiac ganglion of the crab, Cancer borealis.." J Exp Biol 210. (2007): 2873-2884.

Fu, Q., Tang, L.S., Marder, E., and Li, L.. "Mass spectrometric characterization and physiological actions of VPNDWAHFRGSWamide, a novel B type allatostatin in the crab, Cancer borealis,." J. Neurochem 101. (2007): 1099-1107.

Marder, E. "Eve Marder. Interview." Curr Biol 17. 1 (2007): R5-7.

Marder, E. and Bucher, D.. "Understanding circuit dynamics using the stomatogastric nervous system of lobsters and crabs." Annu Rev Physiol 69. (2007): 291-316.

Marder, E., Tobin, A.-E., and Grashow, R.. "How tightly tuned are network parameters? Insight from computational and experimental studies in small rhythmic motor networks.." Progress in Brain Research 165. (2007): 195-202.

Marder, Eve. "Searching for Insight: Using Invertebrate Nervous Systems to Illuminate Fundamental Principles in Neuroscience.." Invertebrate Nervous Systems. Ed. North, G. and Greenspan, R.J.,. Cold Spring Harbor: Cold Spring Harbor Laboratory Press, 2007. 1-18.

Schulz, D.J., Goaillard, J-M, and Marder, E.. "Quantitative expression profiling of identified neurons reveals cell-specific constraints on highly variable levels of gene expression.." Proc Natl Acad Sci (USA) 104. (2007): 13187- 13191.

Billimoria, C. P., DiCaprio, R. A., Birmingham, J. T., Abbott, L. F., Marder, E. "Neuromodulation of spike-timing precision in sensory neurons." J Neurosci 26. 22 (2006): 5910-9.

Bucher, D., Taylor, A. L., Marder, E. "Central pattern generating neurons simultaneously express fast and slow rhythmic activities in the stomatogastric ganglion." J Neurophysiol 95. 6 (2006): 3617-32.

Cruz-Bermudez, N. D., Fu, Q., Kutz-Naber, K. K., Christie, A. E., Li, L., Marder, E. "Mass spectrometric characterization and physiological actions of GAHKNYLRFamide, a novel FMRFamide-like peptide from crabs of the genus Cancer." J Neurochem (2006).

Goaillard, J. M., Marder, E. "Dynamic clamp analyses of cardiac, endocrine, and neural function." Physiology (Bethesda) 21. (2006): 197-207.

Marder, E. "Neurobiology: extending influence." Nature 441. 7094 (2006): 702-3.

Marder, E. "Rejecting arrogance." Curr Biol 16. 3 (2006): R70.

Marder, E. "Rejecting arrogance." Curr Biol 16. 3 (2006): R70.

Marder, E., Bucher, D. "Understanding Circuit Dynamics Using the Stomatogastric Nervous System of Lobsters and Crabs." Annu Rev Physiol (2006).

Marder, E., Goaillard, J. M. "Variability, compensation and homeostasis in neuron and network function." Nat Rev Neurosci 7. 7 (2006): 563-74.

Marder, E., Strick, P. L. "Motor systems. Editorial Overview." Curr Opin Neurobiol 16. 6 (2006): 601-3.

Schulz, D. J., Goaillard, J. M., Marder, E. "Variable channel expression in identified single and electrically coupled neurons in different animals." Nat Neurosci 9. 3 (2006): 356-62.

Schulz, D. J., Goaillard, J. M., Marder, E. "Variable channel expression in identified single and electrically coupled neurons in different animals." Nat Neurosci 9. 3 (2006): 356-62.

Taylor, A. L., Hickey, T. J., Prinz, A. A., Marder, E. "Structure and visualization of high-dimensional conductance spaces." J Neurophysiol 96. 2 (2006): 891-905.

Thirumalai, V., Prinz, A. A., Johnson, C. D., Marder, E. "Red pigment concentrating hormone strongly enhances the strength of the feedback to the pyloric rhythm oscillator but has little effect on pyloric rhythm period." J Neurophysiol 95. 3 (2006): 1762-70.

Billimoria, C. P., Li, L., Marder, E. "Profiling of neuropeptides released at the stomatogastric ganglion of the crab, Cancer borealis with mass spectrometry." J Neurochem 95. 1 (2005): 191-9.

Bucher, D., Prinz, A. A., Marder, E. "Animal-to-animal variability in motor pattern production in adults and during growth." J Neurosci 25. 7 (2005): 1611-9.

Bullock, T. H., Bennett, M. V., Johnston, D., Josephson, R., Marder, E., Fields, R. D. "Neuroscience. The neuron doctrine, redux." Science 310. 5749 (2005): 791-3.

Marder, E., Bucher, D., Schulz, D. J., Taylor, A. L. "Invertebrate central pattern generation moves along." Curr Biol 15. 17 (2005): R685-99.

Marder, E., Rehm, K. J. "Development of central pattern generating circuits." Curr Opin Neurobiol 15. 1 (2005): 86-93.

Pulver, S. R., Bucher, D., Simon, D. J., Marder, E. "Constant amplitude of postsynaptic responses for single presynaptic action potentials but not bursting input during growth of an identified neuromuscular junction in the lobster, Homarus americanus." J Neurobiol 62. 1 (2005): 47-61.

Soto-Trevino, C., Rabbah, P., Marder, E., Nadim, F. "Computational model of electrically coupled, intrinsically distinct pacemaker neurons." J Neurophysiol 94. 1 (2005): 590-604.

Christie, A. E., Stein, W., Quinlan, J. E., Beenhakker, M. P., Marder, E., Nusbaum, M. P. "Actions of a histaminergic/peptidergic projection neuron on rhythmic motor patterns in the stomatogastric nervous system of the crab Cancer borealis." J Comp Neurol 469. 2 (2004): 153-69.

Destexhe, A., Marder, E. "Plasticity in single neuron and circuit computations." Nature 431. 7010 (2004): 789-95.

Goaillard, J. M., Schulz, D. J., Kilman, V. L., Marder, E. "Octopamine modulates the axons of modulatory projection neurons." J Neurosci 24. 32 (2004): 7063-73.

Mahadevan, A., Lappe, J., Rhyne, R. T., Cruz-Bermudez, N. D., Marder, E., Goy, M. F. "Nitric oxide inhibits the rate and strength of cardiac contractions in the lobster Homarus americanus by acting on the cardiac ganglion." J Neurosci 24. 11 (2004): 2813-24.

Marder, E. "Welcome theory." J Neurophysiol 91. 6 (2004): 2389.

Prinz, A. A., Abbott, L. F., Marder, E. "The dynamic clamp comes of age." Trends Neurosci 27. 4 (2004): 218-24.

Prinz, A. A., Bucher, D., Marder, E. "Similar network activity from disparate circuit parameters." Nat Neurosci 7. 12 (2004): 1345-52.

Goaillard, J. M., Marder, E. "Exciting guts with GABA." Nat Neurosci 6. 11 (2003): 1121-2.