DegreesGeorg August University of Göttingen, Ph.D.
Georg August University of Göttingen, M.A.
University of Zulia, B.S.
ExpertiseProkaryotic and Eukaryotic voltage gated ion channel biophysics.
Electrophysiology, Molecular Biology, Biochemistry. Cell biology. Confocal MIcroscopy
Conotoxin interaction and regulation of ion channel function in vitro and in vivo.
ProfileWith the help of several electropgyisiological techniques I
am dedicated to explore structural and functional aspects of various ion channels. Such research is of great importance in the elucidation of the physiological roles of specific channel proteins, the signaling pathways they participate in, as well as their regulation in health and disease.
Finol- Urdaneta, Rocio K., Wang Y, Al-Sabi A, Zhao C, Noskov SY, French RJ.. "Sodium channel selectivity and conduction: Prokaryotes have devised their own molecular strategy.." J Gen Physiol. 2014 Feb;143. (2) (2014): 157-71..
Finol-Urdaneta RK, Remedi MS, Raasch W, Becker S, Clark RB, Strüver N, Pavlov E, Nichols CG, French RJ, Terlau H.. "Block of Kv1.7 potassium currents increases glucose-stimulated insulin secretion." 2012 May (Epub 2012 Mar 21).
French RJ, Finol-Urdaneta RK.. "Open-state stabilization in Kv channels: voltage-sensor relaxation and pore propping by a bound ion.." 2012 Nov. (Epub 2012 Oct 15).
Chen P, Dendorfer A, Finol-Urdaneta RK, Terlau H, Olivera BM.. "Biochemical characterization of kappaM-RIIIJ, a Kv1.2 channel blocker: evaluation of cardioprotective effects of kappaM-conotoxins.." J Biol Chem 285(20). (20) (2010): 14882-9.
Finol-Urdaneta RK, McArthur JR, Juranka PF, French RJ, Morris CE.. "Modulation of KvAP unitary conductance and gating by 1-alkanols and other surface active agents.." Biophys J. 98. (5) (2010): 762-72.
Finol-Urdaneta RK, Strüver N, Terlau H.. "Molecular and Functional Differences between Heart mKv1.7 Channel Isoforms.." J Gen Physiol. 128. (1) (2006): 133-45..