Sacha Nelson

Title

Professor of Biology

Biology
Health: Science, Society, and Policy
Volen National Center for Complex Systems

Expertise

Synaptic integration in the visual cortex.

Degrees

University of California, San Diego, PhD.-M.D

University of California, San Diego, Ph.D.

Brown University, B.A.

Brown University, B.S.

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Contact

Email:	nelson@brandeis.edu
Phone:	781-736-3181
Office:	Carl J. Shapiro Science Center, 1-21

Awards and Honors

GEAR (Grant of Excellence to Accellerate Research) award, Rett Syndrome Research Foundation (2007)

Society for Neuroscience Special Lecture (2005)

Henry Strage Award for Aspiring Young Science Faculty (1999)

Alfred P. Sloan Research Fellowship (1996)

Lange Medical Student Award, Medical Scientist Training Program (1991)

National Institutes of Health Postdoctoral Fellowship (1991 - 1994)

Independent Concentration Prize (1983)

Courses Taught

NBIO	146a	The Neurobiology of Human Disease
NBIO	148b	Cellular Neuroscience
NBIO	150a	Autism and Human Developmental Disorders

Scholarship

95. Katz D.M., Berger-Sweeney J.E., Eubanks J.H., Justice M.J., Neul J.L., Pozzo-Miller L., Blue M.E., Christian D., Crawley J.N., Giustetto M., Guy J., Howell C.J., Kron M., Nelson S.B., et al.. "Preclinical research in Rett syndrome: Setting the foundation for translational success.." Dis. Mod. & Mech. 5. (2013): 733-745.

Blackman M.P., Djukic B., Nelson S.B., and Turrigiano G.G.. "A Critical and Cell-Autonomous Role for MeCP2 in Synaptic Scaling Up.." J. Neurosci. 32. (2013): 13529-13536.

DeFelipe et al.. "New insights into the classification and nomenclature of cortical GABAergic interneurons.." Nature Rev. Neurosci. 14. (2013): 202-16.

Huang C.C., Sugino K., Shima Y., Guo C., Bai S., Mensh B.D., Nelson S.B., and Hantman A.W.. "Convergence of corollary discharge and proprioceptive streams onto multimodal cerebellar granule cells.." eLife 2. (2013): e00400.

Nelson, Sacha B. ; Ashe, Karen H.. "Neurobiology of Disease.." Curr. Op. Neurobiol. 21. (2012): 823-6.

Boggio K.J., Obasuyi E., Sugino K., Nelson S.B., Agar N.Y. and Agar J.N.. "Recent Advances in Single-Cell MALDI Mass Spectrometry Imaging and Potential Clinical Impact.." Expert Rev. Proteomics 8. (2011): 591-604.

Okaty B.W. and Nelson S.B.. "The maturation of firing properties of forebrain GABAergic interneurons." Comprehensive Encyclopedia of Developmental Neuroscience. 2011.

Okaty B.W., Sugino K., Hempel C.M., Nelson S.B.. "A quantitative comparison of cell-type-specific microarray gene expression profiling methods in the mouse brain.." PLOS One 6. (2011): e16493.

Okaty B.W., Sugino K., and Nelson S.B.. "Transcriptomics in the brain." J. Neurosci. 31. (2011): 6939-43.

Rutlin M and Nelson S.B.. "MeCP2: phosphorylated locally, acting globally.." Neuron 72. 1 (2011): 3-5.

Sacha Nelson and Ken Sugino. Methods for Suppression PCR. Patent US Provitional Patent Application 047364-070820-P.

Taniguchi H, He M., Wu P., Kim S., Paik R., Sugino K., Kvitsani D., Fu Y., Lin Y., Lu J., Nelson S.B., Huang Z.J.. "A resource of Cre driver lines for genetic targeting of GABAergic neurons in cerebral cortex.." Neuron 71. 6 (2011): 995-1013.

Luo L, Rodriguez E, Jerbi K, Lachaux JP, Martinerie J, Corbetta M, Shulman GL, Piomelli D, Turrigiano GG, Nelson SB, Joëls M, de Kloet ER, Holsboer F, Amodio DM, Frith CD, Block ML, Zecca L, Hong JS, Dantzer R, Kelley KW, Craig AD. "Ten years of Nature Reviews Neuroscience: insights from the highly cited.." Nat Rev Neurosci 11. (2010): 718-26.

Miller M.N., Okaty B.W., Kato S. and Nelson S.B.. "Activity dependent-changes in the firing properties of neocortical fast-spiking interneurons in the absence of large changes in gene expression." Dev. Neurobiol. 71. (2010): 62-70.

Dani V.S. and Nelson S.B.. "Intact long-term potentiation but reduced connectivity between neocortical layer 5 pyramidal neurons in a mouse model of Rett syndrome." J. Neurosci. 29. (2009): 11263-70.

Kadener S., Menet J.S., Sugino K., Horwich M.D., Weissbein U., Nawathean P., Vagin V.V., Zamore P.D., Nelson S.B., Rosbash M.. "A role for microRNAs in the Drosophila circadian clock.." Genes Dev. 23. (2009): 2179-91.

Kadener S., Rodriguez J., Abruzzi K.C., Khodor Y.L., Sugino K., Marr M.T. 2nd, Nelson S., and Rosbash M.. "Genome-wide identification of targets of the drosha-pasha/DGCR8 complex.." RNA 15. 4 (2009): 537-45.

Nagoshi E., Sugino K., Kula E., Okazaki E., Tachibana T., Nelson S.B. and Rosbash M.. "Gene expression dissection of the circadian neuronal circuit of drosophila." Nature Neurosci. 13. (2009): 60-68.

Okaty B.W. , Miller M.N., Sugino K., Hempel C.M. and Nelson S.B.. "Transcriptional and electrophysiological maturation of neocortical fast-spiking GABAergic interneurons.." J. Neurosci. 29. (2009): 7040-52.

Taneja P., Ojier M., Brooks-Harris G., Katz D.M. and Nelson S.B.. "Pathophysiology of locus coeruleus neurons in a mouse model of Rett Syndrome." J. Neurosci. 29. (2009): 12187-95.