Bassine Science Building, 202
DegreesMassachusetts Institute of Technology, Ph.D.
Yale University, B.A.
ExpertiseBiology education, molecular biology, genetics, protein biochemistry
ProfileI now have the enviable position of teaching and mentoring hundreds of students who are majoring in biology, but I was not a biology major myself. I majored in "Molecular Biophysics and Biochemistry" at Yale, and only really became a Biologist as a graduate student at MIT.
During my graduate student years, most of my energy was focused on my research: biochemical and genetic experiments to better understand the roles, activity, and regulation of a particular protein from yeast (and also found in humans) which enables the error-free copying of UV-damaged DNA molecules. However, I was also already deeply interested in teaching. I learned a tremendous amount about teaching by TAing, and I found additional opportunities to engage in conversations about teaching and learning, through the MIT HHMI Education Group. After completing my PhD, while I continued my research, my focus turned to teaching. I taught introductory biology at MIT for a semester as a Technical Instructor, worked for a couple of years teaching in the High School Outreach Program at the Broad Institute of MIT and Harvard, and taught Biochemistry at Suffolk University.
I have been at Brandeis for nearly two years. I teach the introductory course in Genetics and Genomics, Biol14a, which is taken by many first- and second-year undergraduate students. I also teach courses in molecular biology and cancer biology. In my second year, I have the honor of being one of the Davis Fellows, a group of faculty working together to share and develop our best practices in teaching.
|BIOL||14a||Genetics and Genomics|
|BIOL||150b||DNA: Mechanisms and Research|
|BIOL||172b||Growth Control and Cancer|
|BISC||9b||Biology of Cancer|
Kim YI, Levchenko I, Fraczkowska K, Woodruff RV, Sauer RT, Baker TA. "Molecular determinants of complex formation between Clp/Hsp100 ATPases and the ClpP peptidase.." Nat Struct Biol 8. 3 (2013): :230-3.
Waters LS, Minesinger BK, Wiltrout ME, D'Souza S, Woodruff RV, Walker GC.. "Eukaryotic translesion polymerases and their roles and regulation in DNA damage tolerance.." Microbiol Mol Biol Rev 73. 1 (2013): 134-54.
Woodruff RV, Bomar MG, D'Souza S, Zhou P, Walker GC.. "The unusual UBZ domain of Saccharomyces cerevisiae polymerase η.." DNA Repair (Amst) 9. 11 (2013): 1130-41.
Zhong X, Malhotra R, Woodruff R, Guidotti G.. "Mammalian plasma membrane ecto-nucleoside triphosphate diphosphohydrolase 1, CD39, is not active intracellularly. The N-glycosylation state of CD39 correlates with surface activity and localization.." J Biol Chem 276. 44 (2013): 41518-25.
Kosarek JN, Woodruff RV, Rivera-Begeman A, Guo C, D'Souza S, Koonin EV, Walker GC, Friedberg EC.. "Comparative analysis of in vivo interactions between Rev1 protein and other Y-family DNA polymerases in animals and yeasts.." DNA Repair (Amst) 7. 3 (2008): 439-51.