List of Events



MRSEC SEMINARS-EVENTS

MRSEC Seminars are normally held at 4:00 p.m.  in Abelson 229, unless otherwise noted.
Find  Abelson-Bass-Yalem building on the  interactive map.
________________________________________________

February 9, 2016
Room: Abelson 333
Time: 10 am
Event: MRSEC Seminar
Speaker: Marilia Barros, Carnegie Mellon
Title: Revealing the Molecular and Structural Basis of Retroviral Assembly and Endolysin PlyC Membrane Translocation
Abstract: Numerous biological processes are either triggered by or result in the formation of protein-lipid complexes at the membrane.  The study on the interactions between lipids and proteins is fundamental to gaining insights into the physical aspects of biological processes. We investigated molecular-scale aspects of such membrane interactions using sparsely-tethered lipid bilayer membranes (stBLMs). Applying complementary surface-sensitive techniques such as surface plasmon resonance (SPR) and neutron reflectometry, we  examined  the  details  of  two-stage interaction - surface adsorption and bilayer insertion - and demonstrate the first steps towards a mechanistic understanding of how the endolysin PlyC binding domain, PlyCB, initiates membrane translocation. We also assessed the specific roles of electrostatic, hydrophobic and lipid-specific contributions to HIV-1 matrix (MA) membrane coupling aiming to understand the mechanisms that lead to the recruitment of specific lipids into the viral shell. The impact of MA myristoylation was evaluated and the role of cholesterol was assessed in promoting protein affinity to the bilayer. The molecular level details reported here provide a better understanding of the lipid interactions of MA and their implications for proper Gag membrane association and retroviral particle assembly.




February 12, 2016
Room: Rosenstiel Penthouse
Time: 5:30 pm
Event: MRSEC Social Hour, TGITacos
*Grad students and postdocs only*







February 18, 2016
Room: Abelson 229
Time: 4 pm
Event: MRSEC Seminar
Speaker: Madison Krieger, Brown University
Title: TBA
Abstract: TBA









February 22, 2016
Room: Abelson 307
Event: MRSEC Executive Committee
Time: 9:30 am











March 11, 2016
Room: Rosenstiel Penthouse
Time: 5:30 pm
Event: MRSEC Social Hour, TGITacos
*Grad students and postdocs only*

March 21, 2016
Room: Abelson 307
Event: MRSEC Executive Committee
Time: 9:30 am









April 8, 2016
Room: Rosenstiel Penthouse
Time: 5:30 pm
Event: MRSEC Social Hour, TGITacos
*Grad students and postdocs only*



April 11, 2016
Room: Abelson 307
Event: MRSEC Executive Committee
Time: 9:30 am







May 13, 2016
Room: Rosenstiel Penthouse
Time: 5:30 pm
Event: MRSEC Social Hour, TGITacos
*Grad students and postdocs only*