Wangh Laboratory

Web Sites

• Molecular Beacons 
  A new tool for increasing the effectiveness and lowering the cost of clinical diagnostic assays.
• Stephen A. Bustin
  Real-time PCR is a variation of the polymerase chain reaction (PCR) that allows simultaneous (i.e., in real-time) amplification and detection of DNA templates.

Partners

• Smiths Detection and Diagnostics
  Rapid on-site identification of animal diseases by veterinarians and human diseases in hospital screening programs.
• Arizona State University (Microscale Life Sciences Center)
  The goal of the MLSC is to develop instruments that can measure multiple parameters in living cells in real time. This will allow researchers to correlate cellular events with known genomic information and promises to open up entirely new fields of research. By studying many cell types, we avoid the heterogeneity currently hampering disease diagnosis. As the science advances, we will focus on genomics and health in cells. The impact of this research includes improving our understanding and treatment of cancer, heart disease and stroke.

Presentations/Podcasts

• LATE-PCR and Its Related Technologies
  Professor Wangh interviewed by Genetic Engineering and Biotechnology, Feb. 22, 2007

Publications

• Use of LATE-PCR Outside Brandeis (pdf)
  Szemes, M., Bonants, P., de Weerdt, M., Baner, J., Landegren, U., and Schoen, C.D. (2005) Diagnostic application of padlock probes - multiplex detection of plant pathogens using universal microarrays, Nucleic Acids Research, 33:8.
• Use of PurAmp Outside Brandeis (pdf)
  Nolan, T., Hands, R.E., and Bustin, S.A. (2006) Quantification of mRNA using real-time RT-PCR, Nature Protocols, 1:3.