Bing Xu
Degrees
University of Pennsylvania, Ph.D.Nanjing University, M.S.
Nanjing University, B.A.
Expertise
Biomaterials chemistry; enzymatic noncovalent synthesis; functional molecular and nanomaterials for biomedicine.Profile
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Our research focuses on the interdisciplinary frontier of materials chemistry--enzymatic noncovalent synthesis. We integrate the knowledge and techniques in chemistry, molecular cell biology, materials science, and nanotechnology to design new molecular biofunctional materials, including nanomaterials, for the exploration in biomedicine (e.g., molecular drug delivery, cancer therapy, biomedical diagnostics, and biomimetics), and other fundamental problems in nanoscience and biological science. Webpage
Courses Taught
| CHEM | 69a | Advanced Laboratory: Materials Chemistry |
| CHEM | 91g | Introduction to Research Practice |
| CHEM | 132b | Advanced Organic Chemistry: Spectroscopy |
| CHEM | 160a | Materials Chemistry: Molecular Foundation for Nanobiotechnology |
Awards and Honors
“Highly-cited researchers 2016” in chemistry, Thompson Reuters (2017)
“Highly-cited researchers 2015” in chemistry, Thompson Reuters (2016)
“Highly-cited researchers 2014” in chemistry, Thompson Reuters (2015)
DuPont Asian & European Young Investigator Award (2001)
NIH Postdoctoral Fellowship (1997)
Glenn Brown Award of International Liquid Crystal Society (1996)
Scholarship
Adrianna N. Shy, Beom Jin Kim, and Bing Xu. "Enzymatic Noncovalent Synthesis of Supramolecular Soft Matters for Biomedical Applications." Matter 1. (2020): 1127-1147.
Beom Jin Kim, Dongsik Yang, and Bing Xu* “Emerging Applications of Supramolecular Peptide Assemblies” Trends in Chemistry 2020, 2, 71-83.. "Emerging Applications of Supramolecular Peptide Assemblies." Trends in Chemistry 2. (2020): 71-83..
Hongjian He, Jiaqi Guo, Xingyi Lin and Bing Xu. "Enzyme-Instructed Assemblies Enable Mitochondria Localization of H2B in Cancer Cells." Angew. Chem. Int. Ed. 59. (2020): 9330-9334.
Hongjian He, Shuang Liu, Difei Wu, and Bing Xu. "Enzymatically-Formed Peptide Assemblies Sequestrate Proteins and Relocate Inhibitors for Selectively Killing Cancer Cells." Angewandte Chemie International Edition 59. (2020): 16445-16450.
Hongjian He, Weiyi Tan, Jiaqi Guo, Meihui Yi, Adrianna N. Shy and Bing Xu. "Enzymatic Noncovalent Synthesis." Chemical Reviews 18. (2020): 9994-10078.
Hongjian He, Xinyi Lin, Difei Wu, Jiaqing Wang, Jiaqi Guo, Douglas R. Green, Hongwei Zhang, and Bing Xu. "Enzymatic Noncovalent Synthesis for Mitochondrial Genetic Engineering of Cancer Cells." Cell Reports Physical Science 1. (2020): 100270.
Jiaqing Wang, Deani L. Cooper, Wenjun Zhan, Difei Wu, Hongjian He, Shenghuan Sun, Susan T. Lovett, Bing Xu. "Diglycine Enables Rapid Intrabacterial Hydrolysis for Activating Anbiotics against Gram-negative Bacteria." Angewandte Chemie International Edition 58. (2020): 10631-10634.
Zhaoqianqi Feng, Huaimin Wang, Fengbin Wang, Younghoon Oh, Cristina Berciu, Qiang Cui,* Edward H. Egelman* and Bing Xu*. "Artificial Intracellular Filaments." Cell Reports Physical Science 1. (2020): 10085.
Zhaoqianqi Feng, Huaimin Wang, Meihui Yi, Chieh-Yun Lo, Ashanti Sallee, Jer-Tsong Hsieh and Bing Xu. "Instructed-Assembly of Small Peptides Inhibits Drug-Resistant Prostate Cancer Cells." Peptide Science 1. (2020): e24123..
Zhaoqianqi Feng, Xiuguo Han, Huaimin Wang, Tingting Tang, and Bing Xu. "“Enzyme-Instructed Peptide Assemblies Selectively Inhibit Bone Tumors." Chem 5. (2020): 2442-2449..
Huaimin Wang, Zhaoqianqi Feng, Cuihong Yang, Jinjian Liu, Jamie E. Medina, S. Ali Aghvami, Daniela M. Dinulescu, Jianfeng Liu, Seth Fraden, and Bing Xu. "Unraveling the Cellular Mechanism of Assembling Cholesterols for Selective Cancer Cell Death." Molecular Cancer Research 17. (2019): 907-917.
Huaimin Wang, Zhaoqianqi Feng, and Bing Xu. "Assemblies of Peptides in Complex Environment and Their Applications." Angewandte Chemie International Edition 58. (2019): 10423-10432..
Huaimin Wang, Zhaoqianqi Feng, and Bing Xu. "Instructed-Assembly as Context-Dependent Signals for Death and Morphogenesis of Cells." Angew. Chem. Int. Ed. 58. (2019): 5567-5571.
Huaimin Wang, Zhaoqianqi Feng, and Bing Xu. "Intercellular Instructed-Assembly Mimics Protein Dynamics to Induce Cell Spheroids." Journal of the American Chemical Society 141. (2019): 7271-7274..
He, H. J.; Wang, J. Q.; Wang, H. M.; Zhou, N.; Green, D.; Xu, B.. "Enzymatic Cleavage of Branched Peptides for Targeting Mitochondria." J. Am. Chem. Soc. 140. (2018): 1215-1218..
Jie Li; Ziqing Zhan; Xuewen Du; Jiaqing Wang; Brandon Hong; Bing Xu. "Selection of Secondary Structures of Heterotypic Supramolecular Peptide Assemblies by an Enzymatic Reaction." Angew. Chem. Int. Ed. 57. (2018): 11716-11721.
Wang, H. M.; Feng, Z. Q. Q.; DelSignore, S. J. ; Rodal, A. A.; Xu, B.. "Active Probes for Imaging Membrane Dynamics of Live Cells with High Spatial and Temporal Resolution over Extended Timescales and Areas." J. Am. Chem. Soc. 140. (2018): 3505-3509.
Wang,H. M.; Feng, Z. Q. Q.; Qin, Y. N.; Wang, J. Q.; Xu, B.. "Nucleopeptide Assemblies Selectively Sequester ATP in Cells to Increase the Efficcay of Doxorubicin." Angew. Chem. Int. Ed. 2018 57. (2018): 4931-4935.
Zhaoqianqi Feng, Huaimin Wang and Bing Xu. "Instructed-Assembly of Peptides for Intracellular Enzyme Sequestration." J. Am. Chem. Soc. 140. (2018): 16433-16437.
Zhaoqianqi Feng; Huaimin Wang; Shiyu Wang; Qiang Zhang; Xixiang Zhang; Avital A. Rodal; Bing Xu. "Enzymatic Assemblies Disrupt the Membrane and Target Endoplasmic Reticulum for Selective Cancer Cell Death." J. Am. Chem. Soc. 140. (2018): 9566-9573.
Zhou, J.; Du, X. W.; Chen, X. Y.; Wang, J. Q.; Zhou, N.; Wu, D. F.; Xu, B.. "Enzymatic Self-Assembly Confers Exceptionally Strong Synergism with NF-kB Targeting for Selective Necroptosis of Cancer Cells." J. Am. Chem. Soc. 140. (2018): 2301-2308..
Du, X. W.; Zhou, J.; Wang, H. M.; Shi, J. F.; Kuang, Y.; Zeng, W; Yang, Z. M.; Xu, B.. "In Situ Generated D‐Peptidic Nanofibrils as Multifaceted Apoptotic Inducers to Target Cancer Cells." Cell Death & Diseases 8. (2017): ,e2614..
Feng, Z. Q. Q.; Wang, H. M.; Chen, X. Y.; Xu, B.. "Self-Assembling Ability Determines the Activity of Enzyme-Instructed Self-Assembly for Inhibiting Cancer Cells"." J. Am. Chem. Soc. 139. (2017): 15377-15384..
Feng, Z. Q. Q.; Wang, H. M.; Zhou, R.; Li, J.; and Xu, B.. "Enzyme-Instructed Assembly and Disassembly Processes for Targeting Down-Regulation in Cancer Cells." J. Am. Chem. Soc. 139. (2017): 3950-3953.
Feng, Z. Q. Q.; Zhang, T. F.; Wang, H. M.; Xu, B.. "“Supramolecular Catalysis and Dynamic Assemblies for Medicine." Chem. Soc. Rev. 46. (2017): 6470-6479.
Li, J.; Du, X. W.; Hashim, S.; Shy, A.; Xu, B.. "Aromatic-Aromatic Interactions Enable α-Helix to β-Sheet Transition of Peptides to Form Supramolecular Hydrogels." J. Am. Chem. Soc. 139. (2017): 71-74..
Wang, H. M.; Feng, Z. Q. Q.; Lu, A.; Jiang, Y. J.; Wu, H.; Xu, B.. "Instant Hydrogelation Inspired by Inflammasomes." Angew. Chem. Int. Ed. 56. (2017): 7579-7583..
Wang, H. M.; Feng, Z. Q. Q.; Xu, B.. "Bioinspired self-assembly of small molecules in cell milieu." Chem. Soc. Rev. 46. (2017): 2421-2436..
Wang, H. M.; Shi, J. F.; Feng, Z. Q. Q; Zhou, R.; Wnag, S. Y.; Rodal, A. A.; Xu, B.. "An in-situ Dynamic Continuum of Supramolecular Phosphoglycopeptides Enables Formation of 3D Cell Spheroids." Angew. Chem. Int. Ed. 56. (2017): 7579-7583.
Zhou, J.; Li, J.; Du, X. W.; Xu, B.. "Supramolecular Biofunctional Materials." Biomaterials 129. (2017): 1-27.
Zhou, N.; Cao, X. Y.; Du, X. W.; Wang, H. M.; Wang, M.; Liu, S.; Nguyen, K.; Schmidt-Rohr, K.; Xu, Q. B.; Liang, G. L.; Xu, B.. "Hyper-Crosslinkers Impart Dual Responsive Polymeric Nanogels with Unusual Volume Change." Angew. Chem. Int. Ed. 56. (2017): 2623-2627.
Haburcak, R.; Shi, J. F.; Du, X. W.; Yuan, D.; Xu, B.. "Ligand-Receptor Interaction Modulates the Energy Landscape of Enzyme-Instructed Self-Assembly of Small Molecules." J. Am. Chem. Soc. 138. (2016): 15397–15404.
Wang, H. M.; Feng, Z. Q. Q.; Wang, Y. Z.; Zhou, R.; Yang, Z. M.; Xu, B.. "Integrating Enzymatic Self-Assembly and Mitochondria Targeting for Selectively Killing Cancer Cells without Acquired Drug Resistance." J. Am. Chem. Soc. 138. (2016): 16046−16055.
Wang, H. M.; Feng, Z. Q.Q.; Wu, D. D.; Rigney, M.; Zhou, J.; Jiang, Y. J.; Xu, B.. "Enzyme-Regulated Supramolecular Assemblies of Cholesterol Conjugates against Drug-Resistant Ovarian Cancer Cells." J. Am. Chem. Soc. 138. (2016): 10758−10761.
Zhou, J.; Du, X. W.; Berciu, C.; He, H. J.; Shi, J. F.; Nicastro, D.; Xu, B.. "Enzyme-Instructed Self-Assembly for Spatiotemporal Profiling of the Activities of Alkaline Phosphatases of Live Cells." Chem 1. (2016): 246-263.
Zhou, J.; Du, X. W.; Xu, B.. "Regulating the Rate of Molecular Self-Assembly for Targeting Cancer Cells." Angew. Chem. Int. Ed. 55. (2016): 5770-5775.
Zhou, J.; Du, X. W.; Yamagata, N.; Xu, B.. "Enzyme-Instructed Self-Assembly of Small D-Peptides as a Multiple-Step Process for Selectively Killing Cancer Cells." J. Am. Chem. Soc. 138. (2016): 3813-3823.
Du, X. W.; Zhou, J.; Shi, J. F.; Xu, B.. "Supramolecular Hydrogelators and Hydrogels: From Soft Matter to Molecular Biomaterials." Chem. Rev. 115. (2015): 13165-13307.
Li, J.; Kuang, Y.; Shi, J. F.; Zhou, J.; Medina, J. E.; Zhou, R.; Yuan, D.; Yang, C. H.; Wang, H. M.; Yang, Z. M.; Liu, J. F.; Dinulescu, D. M. and Xu, B.. "“Enzyme-Instructed Intracellular Molecular Self-assembly to Boost Activity of Cisplatin against Drug-Resistant Ovarian Cancer Cells." Angew. Chem. Intl. Ed., 54. (2015): 13307-13311.
Shi, J. F.; Du, X. W.; Huang, Y. B.; Zhou, J.; Yuan, D.; Wu, D. D.; Zhang, Y.; Haburcak, R.; Epstein, I. R.; Xu, B.. "Ligand-Receptor Interaction Catalyzes the Aggregation of Small Molecules to Induce Cell Necroptosis." J. Am. Chem. Soc. 137. (2015): 26-29.
Shi, J. F.; Xu, B.. "Nanoscale Assemblies of Small Molecule Control the Fate of Cells." Nano Today, 2015 10. (2015): 615-630.
Yuan, D.; Du, X. W.; Shi, J. F.; Zhou, N.; Zhou, J.; Xu, B.. "Mixing Biomimetic Heterodimers of Nucleopeptides to Generate Biocompatible and Biostable Supramolecular Hydrogels." Angew. Chem. Intl. Ed. 54 (2015): 5705-5708.
Yuan, D.; Shi, J. F.; Du, X. W.; Zhou, N.; Xu, B.. "Supramolecular Glycosylation Accelerates Proteolytic Degradation of Peptide Nanofibrils." J. Am. Chem. Soc. 137. (2015): 10092-10095.
Zhang, Y.; Zhou, N.; Shi, J. F.; Pochapsky, S. S.; Pochapsky, S. S.; Zhang, B.; Zhang, X. X.; Xu, B.. "Unfolding a molecular trefoil derived from a zwitterionic metallopeptide to form self-assembled nanostructures." Nat. Commun. 6. (2015): 6165..
Zhou, J.; Du, X. W.; Li, J.; Yamagata, N.; Xu, B.. "Taurine Boosts Cellular Uptake of Small D-peptides for Enzyme-Instructed Intracellular Molecular Self-assembly." J. Am. Chem. Soc. 137. (2015): 10040-10043.
Zhou, J.; Xu, B.. "Enzyme-Instructed Self-Assembly (EISA): A Multi-Step Process for Potential Cancer Therapy." Bioconjugate Chem. 26. (2015): 987-999.
Du, X. W.; Zhou, J.; Guvench, O.; Sangiorgi, F. O.; Li, X. M.; Zhou, N.; Xu, B.. "Supramolecular Assemblies of A Conjugate of Nucleobase, Amino Acids, and Saccharide Act as Agonists for Proliferation of Embryonic Stem Cells and Development of Zygotes." Bioconjugate Chem 25. (2014): 1031-1035.
Du, X. W.; Zhou, J.; Wu, L. H.; Sun, S. H.; Xu, B.. "Enzymatic Transformation of Phosphate Decorated Magnetic Nanoparticles for Selectively Sorting and Inhibiting Cancer Cells." Bioconjugate Chem. 25. (2014): 2129–2133.
Kuang, Y.; Shi, J. F.; Li, J.; Yuan, D.; Alberti, K. A.; Xu, Q. B.; Xu, B.. "Pericellular Hydrogel/Nanonets Inhibit Cancer Cells." Angew. Chem. Intl. Ed. 53. (2014): 8104-8107.
Kuang,Y.; Long, M. J. C.; Zhou, J.; Shi, J. F.; Gao, Y.; Xu, C.; Hedstrom, L.; Xu, B. "Prion-like Nanofibrils of Small Molecules (PriSM) Selectively Inhibit Cancer Cells by Impeding Cytoskeleton Dynamics." J. Biol. Chem. 289 (2014): 29208.
Zhang, Y.; Zhou, N.; Li, N.; Sun, M.; Kim, D.; Fraden, S. ; Epstein, I. E. ; Xu, B.. "Giant Volume Change of Active Gels under Continuous Flow." J. Am. Chem. Soc. 136. (2014): 7341-7346.
Zhao, F.; Li, J.; Zhou, N.; Sakai, J.; Gao, Y.; Shi, J. F.; Goldman, B.; Browdy, H. M.; Luo, H. R.; Xu, B.. "De Novo Chemoattractants Form Supramolecular Hydrogels for Immunomodulating Neutrophils In Vi." Bioconjugate Chem. 25. (2014): 2116-2122.
Zhou, J.; Du, X. W.; Gao, Y.; Shi, J. F.; Xu, B.. "Aromatic-Aromatic Interactions Enhance Interfiber Contacts for Enzymatic Formation of A Spontaneously Aligned Supramolecular Hydrogel." J. Am. Chem. Soc. 136. (2014): 2970-2973.
Kuang, Y.; Xu, B.. "Nanofibers of Small Hydrophobic Molecules Disrupt Dynamics of Microtubles and Selectively Inhibit Gliobalstoma Cells." Angew. Chem. Int. Ed. 52. (2013): 6944-6948.
Li, J. Y.; Gao, Y.; Kuang, Y.; Shi, J. F.; Du, X. W.; Zhou, J.; Wang, H. M.; Yang, Z. M.; Xu, B.. "Dephosphorylation of D-Peptide Derivatives to Form Biofunctional, Supramolecular Nanofibers/Hydrogels and Their Potential Applications for Intracellular Imaging and Intratumoral Chemotherapy." J. Am. Chem. Soc. 135. (2013): 9907-9914.
Li, J. Y.; Kuang, Y.; Gao, Y.; Du, X. W.; Shi, J. F.; Xu, B.. "D-Amino Acids Boost the Selectivity and Confer Supramolecular Hydrogels of a Non-steroidal Anti-inflammatory Drug (NSAID)." J. Am. Chem. Soc. 135. 2 (2013): 542-545.
Li, J. Y.; Li, X. M.; Kuang, Y.; Gao, Y.; Du, X. W.; Shi, J. F.; Xu B.. "Self-delivery Multifunctional Anti-HIV Hydrogels for Sustained Release." Adv. Healthcare Mater. 2. (2013): 1586-1590.
Zhang, Y.; Zhang, B.; Kuang, Y.; Gao, Y.; Shi, J.; Zhang, X. X.; Xu, B.. "A Redox Responsive, Fluorescent Supramolecular Metallohydrogel Consists of Nanofibers with Single-Molecule Width." J. Am. Chem. Soc. 135. 135 (2013): 5008-5011.
Zhang, Y.; Zhou, N.; Akella, S.; Kuang, Y.; Kim, D.; Schwartz, A.; Bezpalko, M.; Foxman, B. M.; Fraden, S.; Epstein, I. R; Xu, B.. "Active Cross-linkers that Lead to Active Gels." Angew. Chem. Int. Ed. 52. (2013): 11494-11498.
Gao, Y.; Shi, J. F.; Yuan, D.; Xu, B.. "Imaging enzyme-triggered self-assembly of small molecules inside live cells." Nat. Commun. 3. (2012): 1033.
Li, X. M.; Kuang, Y.; Lin, H.-C.; Gao, Y.; Shi, J. F.; Xu, B.. "Supramolecular Nanofibers and Hydrogels of Nucleopeptides." Angew. Chem. Intl. Ed. 50. (2011): 9365-9369..
Li, X. M.; Kuang, Y.; Shi, J. F.; Gao, Y.; Lin, H.C.; Xu, B.. "Multifunctional, Biocompatible Supramolecular Hydrogelators Consist Only of Nucleobase, Amino Acid, and Glycoside." J. Am. Chem. Soc., 133. (2011): 17513-17518.
Long, M. J. C.; Pan, Y.; Lin, H.-C.; Hedstrom, L.; Xu, B.. "Cell Compatible Trimethoprim (TMP)-Decorated Iron Oxide Nanoparticles Bind Dihydrofolate Reductase (DHFR) for Magnetically Modulating Focal Adhesion of Mammalian Cells." J. Am. Chem. Soc. 133. (2011): 10006-10009.
Gao, Y., Zhao, F., Wang, Q. G., Zhang, Y., Xu, B.. "Small peptide nanofibers as the matrices of molecular hydrogels for mimicking enzymes and enhancing the activity of enzymes." Chemical Society Reviews 39. 9 (2010): 3425-3433.
Gao, Y.; Yang, Z. M.; Kuang, Y.; Ma, M. L.; Li, J. Y.; Zhao, F.; Xu, B.*. "“Enzyme-instructed Self-assembly of Peptide Derivatives to Form Nanofibers and Hydrogels”." Biopolymers: Peptide Sci 94. (2010): 19-31.
Li, X. M., Li, J. Y., Gao, Y. A., Kuang, Y., Shi, J. F., Xu, B.. "Molecular Nanofibers of Olsalazine Form Supramolecular Hydrogels for Reductive Release of an Anti-inflammatory Agent." Journal of the American Chemical Society 132. 50 (2010): 17707-17709.
Ma, M. L., Kuang, Y., Gao, Y., Zhang, Y., Gao, P., Xu, B.. "Aromatic-Aromatic Interactions Induce the Self-Assembly of Pentapeptidic Derivatives in Water To Form Nanofibers and Supramolecular Hydrogels." Journal of the American Chemical Society 132. 8 (2010): 2719-2728.
Gao JH, Gu HW, Xu B. "Multifunctional Magnetic Nanoparticles: Design, Synthesis, and Biomedical Applications." Acc. Chem. Res 42. 8 (2009): 1097-1107.
Gao Y, Kuang Y, Guo ZF, Guo ZH, Krauss IJ,Xu, Bing. "Enzyme-Instructed Molecular Self-assembly Confers Nanofibers and a Supramolecular Hydrogel of Taxol Derivative." J. Am. Chem. Soc. 131. 38 (2009): 13576-13577.
Gao, J. H.; Xu, B.. "Applications of Nanomaterials inside Cells." Nano Today, 4. (2009): 37-51.
Zhao, F.; Ma, M. L.; Xu, B.. "Molecular Hydrogels of Therapeutic Agents." Chem. Soc. Rev. 38. (2009): 883-891.
Gao, J. H.; Liang, G. L.; Cheung, J.; Pan, Y.; Kuang, Y.; Zhao, F.; Zhang, B.; Zhang, X. X.; Wu, E. X.; Xu, B.. "Multifunctional Yolk-shell Nanoparticles: A Potential MRI Contrast and Anticancer Agent." J. Am. Chem. Soc. 130. (2008): 11828-11833.
Jinhao Gao, Wei Zhang, Pingbo Huang, Bei Zhang, Xixiang Zhang, Bing Xu. "Intracellular Spatial Control of Fluorescent Magnetic Nanoparticles." Journal of the American Chemical Society 130. (2008): 3710-3711.
Zhimou Yang, Gaolin Liang, Bing Xu. "Enzymatic Hydrogelation of Small Molecules." Accounts of Chemical Research 41. 2 (2008): 315-326.
Gao, J. H., Liang, G. L., Zhang, B., Kuang, Y., Zhang, X. X., Xu, B.. "FePt@CoS2 yolk-shell nanocrystals as a potent agent to kill HeLa cells." Journal of the American Chemical Society 129. 5 (2007): 1428-1433.
Gao, J. H., Zhang, B., Gao, Y., Pan, Y., Zhang, X. X., Xu, B.. "Fluorescent Magnetic Nanocrystals by Sequential Addition of Reagents in a One-Pot Reaction: A Simple Preparation for Multifunctional Nanostructures." Journal of the American Chemical Society 129. (2007): 11928-11935.
Wang, Q.G., Yang, Z. M., Zhang, X. Q., Xiao, X. D., Chang, C. K., Xu, B.. "A Supramolecular Hydrogel-Encapsulated Hemin as an Artificial Enzyme to Mimic Peroxidase." Angewandte Chemie-International Edition in English 46. (2007): 4285-4289.
Yang, Z. M., Ho, P. L., Liang, G. L., Chow, K. H., Wang, Q. G., Cao, Y., Guo, Z. H., Xu, B.. "Using beta-lactamase to trigger supramolecular hydrogelation." Journal of the American Chemical Society 129. 2 (2007): 266-267.
Yang, Z. M., Liang, G. L., Guo, Z. F., Guo, Z. H., Xu, B.. "Intracellular Hydrogelation of Small Molecules Inhibits Bacterial Growth." Angewandte Chemie-International Edition in English 46. (2007): 8216-8219.
Yang, Z. M., Xu, K. M., Guo, Z. F., Guo, Z. H., Xu, B.. "Intracellular Enzymatic Formation of Nanofibers Results in Hydrogelation and Regulated Cell Death." Advanced Materials 17. (2007): 3152-3156..
Gao, J. H., Zhang, B., Zhang, X. X., Xu, B.. "Magnetic-dipolar-interaction-induced self-assembly affords wires of hollow nanocrystals of cobalt selenide." Angewandte Chemie-International Edition 45. 8 (2006): 1220-1223.
Gu, H. W., Xu, K. M., Xu, C. J., Xu, B.. "Biofunctional magnetic nanoparticles for protein separation and pathogen detection." Chemical Communications 9 (2006): 941-949.
Wang, L., Yang, Z. M., Gao, J. H., Xu, K. M., Gu, H. W., Zhang, B., Zhang, X. X., Xu, B.. "A biocompatible method of decorporation: Bisphosphonate-modified magnetite nanoparticles to remove uranyl ions from blood." Journal of the American Chemical Society 128. 41 (2006): 13358-13359.
Yang, Z. M., Liang, G. L., Wang, L., Xu, B.. "Using a Kinase/Phosphatase Switch to Regulate a Supramolecular Hydrogel and Forming the Supramolecular Hydrogel in vivo." Journal of the American Chemical Society 128. (2006): 3038-3043.
Zheng, R. K., Gu, H. W., Xu, B., Fung, K. K., Zhang, X. X., Ringer, S. P.. "Self-assembly and self-orientation of truncated octahedral magnetite nanocrystals." Advanced Materials 18. 18 (2006): 2418-+.
Gu, H. W., Yang, Z. M., Gao, J. H., Chang, C. K., Xu, B.. "Heterodimers of nanoparticles: Formation at a liquid-liquid interface and particle-specific surface modification by functional molecules." Journal of the American Chemical Society 127. 1 (2005): 34-35.
Gu, H. W., Zheng, R. K., Zhang, X. X., Xu, B.. "Facile one-pot synthesis of bifunctional heterodimers of nanoparticles: A conjugate of quantum dot and magnetic nanoparticles." Journal of the American Chemical Society 126. 18 (2004): 5664-5665.
Xu, C. J., Xu, K. M., Gu, H. W., Zheng, R. K., Liu, H., Zhang, X. X., Guo, Z. H., Xu, B.. "Dopamine as a robust anchor to immobilize functional molecules on the iron oxide shell of magnetic nanoparticles." Journal of the American Chemical Society 126. 32 (2004): 9938-9939.
Xu, C. J., Xu, K. M., Gu, H. W., Zhong, X. F., Guo, Z. H., Zheng, R. K., Zhang, X. X., Xu, B.. "Nitrilotriacetic acid-modified magnetic nanoparticles as a general agent to bind histidine-tagged proteins." Journal of the American Chemical Society 126. 11 (2004): 3392-3393.
Yang, Z. M., Gu, H. W., Fu, D. G., Gao, P., Lam, J. K., Xu, B.. "Enzymatic formation of supramolecular hydrogels." Advanced Materials 16. 16 (2004): 1440-+.
Zhang, Y., Yang, Z. M., Yuan, F., Gu, H. W., Gao, P., Xu, B.. "Molecular recognition remolds the self-assembly of hydrogelators and increases the elasticity of the hydrogel by 10(6)-fold." Journal of the American Chemical Society 126. 46 (2004): 15028-15029.
Gu, H. W., Ho, P. L., Tong, E., Wang, L., Xu, B.. "Presenting vancomycin on nanoparticles to enhance antimicrobial activities." Nano Letters 3. 9 (2003): 1261-1263.
Gu, H. W., Ho, P. L., Tsang, K. W. T., Wang, L., Xu, B.. "Using biofunctional magnetic nanoparticles to capture vancomycin-resistant enterococci and other gram-positive bacteria at ultralow concentration." Journal of the American Chemical Society 125. 51 (2003): 15702-15703.
Gu, H. W., Xu, C. J., Weng, L. T., Xu, B.. "Solventless polymerization: Spatial migration of a catalyst to form polymeric thin films in microchannels." Journal of the American Chemical Society 125. 31 (2003): 9256-9257.
Yu, H. H., Xu, B., Swager, T. M.. "A proton-doped calix[4]arene-based conducting polymer." Journal of the American Chemical Society 125. 5 (2003): 1142-1143.
Zhang, Y., Gu, H. W., Yang, Z. M., Xu, B.. "Supramolecular hydrogels respond to ligand-receptor interaction." Journal of the American Chemical Society 125. 45 (2003): 13680-13681.
Xing, B. G., Choi, M. F., Xu, B.. "Design of coordination polymer gels as stable catalytic systems." Chemistry-a European Journal 8. 21 (2002): 5028-5032.
Xing, B. G., Yu, C. W., Chow, K. H., Ho, P. L., Fu, D. G., Xu, B.. "Hydrophobic interaction and hydrogen bonding cooperatively confer a vancomycin hydrogel: A potential candidate for biomaterials." Journal of the American Chemical Society 124. 50 (2002): 14846-14847.