Guillermina Ramirez-San Juan

Assistant Professor of Biology

Departments/Programs

Biology
Rosenstiel Basic Medical Sciences Research Center

Degrees

University of Chicago, Ph.D.
National Autonomous University of Mexico, B.S.

Expertise

Biophysics of Cells and Tissues

Profile

My research merges cell and developmental biology with fluid mechanics and active matter to understand how flows are built by arrays of cilia. By studying a variety of multiciliated cells and organisms we aim to elucidate the biophysical mechanisms that link cytoskeletal patterning, cilia patterning and flow generation.

https://livingpatterns.group/

Courses Taught

BIOL	91g	Introduction to Research Practice
BIOL	350a	Graduate Student Research Seminar
PHYS	91g	Introduction to Research Practice
QBIO	120b	Quantitative Biology Instrumentation Laboratory

Scholarship

Ramirez-San Juan, G. R., Mathijssen A.J.T.M., He M., Jan L., Marshall W., and Prakash MRamirez-San Juan, Guillermina. "Multi-scale spatial heterogeneity enhances particle clearance in airway ciliary arrays." Nature Physics (2020).

Fessenden T.B., Beckham Y., Perez-Neut M., Ramirez-San Juan, G. R., Chourasia A.H., MacCleod K.F., Oakes P.W., and Gardel M.L. "Dia1-dependent adhesions are required by epithelial tissues to initiate invasion." The Journal of Cell Biology (2018).

Oakes P.W., Bidone T.C., Beckham Y., Skeeters A.V., Ramirez-San Juan, G. R., Winter S.P., Voth G.A., and Gardel M.L. "Lamellipodium is a myosin-independent mechanosensor." Proceedings of the National Academy of Sciences (2018).

Hissa B., Oakes P.W., Pontes B., Ramirez-San Juan, G. R., and Gardel M.L. "Cholesterol depletion impairs contractile machinery in neonatal rat cardiomyocytes." (2017).

Ramirez-San Juan, G. R., Oakes P.W., and Gardel M.L. "Contact guidance requires spatial control of leading-edge protrusion." Molecular Biology of the Cell (2017).

Cetera* M., Ramirez-San Juan*, G. R., Oakes P.W., Lewellyn L., Fairchild M.J., Tanentzapf G., Gardel M.L., and Horne-Badovinac S.. "Epithelial rotation promotes the global alignment of contractile actin bundles during Drosophila egg chamber elongation." Nature Communications (2014).

Ramirez-San Juan, G. R., Minzoni A.A., and Islas L.D.. "Effects of electrical polarization on the opening rate constant of a voltage-gated ion channel." Phys. Rev. E (2013).