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RBIF 106

Drug Discovery and Development

There are high expectations for bioinformatics to contribute to drug discovery. This course explores issues faced during drug discovery and development. Topics include the drug discovery process, its major players and its origins; scientific principles behind drug properties and actions; target product profiles; disease and drug target selection, sources of drug-like molecules; assays and screening; medicinal chemistry; pharmacology; toxicology; and clinical trials.

At the end of the course, students will be able to:

Apply bioinformatics strategies to identify, characterize, assess and prioritize drug targets and compounds.

Determine the core information needs that support drug discovery decision-making from lab to clinic to market.

Communicate the organization of the drug discovery and development process and the related informatics needs within the process.

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