2021-22 M.R. Bauer Foundation Summary
The 2021-22 M.R. Bauer Foundation, Colloquium Series, Distinguished Lecturer Series and Summer Science Research Fellowship
Letter from the Director
There are signs of renewal; spirits are rising with the retreat of the pandemic. We have come through a historic event, one that will have lasting consequences. Among these, I hope, will be the public's re-engagement with and clear-minded perspective on the importance of science.
The strife and divisions that surround policymaking and governing should not diminish the sacrifices of virologists, immunologists, vaccine developers and many others. For two years, these scientists devoted their extraordinary talents to solving a monumental challenge. In my view, they performed admirably.
As with so many world-changing events, the generation coming of age adopts the sentiment of the time. The pandemic left no one untouched. Students are emerging, most invigorated with fresh purpose, but some still tentative. They see the importance and relevance of their research, and they are trying to embrace the moment.
For the scientific community at Brandeis, we are seeing a re-emergence of the interpersonal collaboration which is the hallmark of this university — the esprit de corps that fuels our research and teaching. The campus is re-energized, and colleagues are once again seeing each other in person rather than by pixel. These professional and social interactions allow for real communication of ideas between fields and labs. Spontaneous, serendipitous encounters may inspire, but it is in meetings where the brainstorming, planning and action really take place. We are fortunate to truly be back to work, and the time away reinforced the knowledge that in-person community is critical.
This work happens through a groundswell of support. The pandemic sparked a deep appreciation for the necessity of public investment in the public welfare — equity, health and research and development — but science needs champions, and friends of Brandeis stood by the university. The M.R. Bauer Foundation continues to support established and emerging scientists across the disciplines. The foundation is joined by generous individuals, graduates, corporations and others who ensure that the Brandeis enterprise remains world-leading. We are grateful for their unyielding commitment.
To not just live, but to thrive; that is a lesson of the pandemic. At Brandeis and beyond, we will strive to ensure that the world is illuminated by science.
Leslie C. Griffith, MD, PhD
Nancy Lurie Marks Professor of Neuroscience and
Director, Volen National Center for Complex Systems
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“What is essential is invisible to the eye.” The beauty of these words from Antoine de Saint-Exupery is in their universal applicability to all aspects of the human existence, including our growing understanding of the machinations of the human body. How do the smallest parts, those that are invisible to the eye, affect the working of the whole?
Signals on the skin can lead either to feelings of reward or feelings of constant pain. The time of day can change the response of a cell to a stimulus. Changes in small molecules can change the activity in an entire network of neurons. Very small differences can have enormous ramifications on how the brain works, how brain systems can become dysfunctional, and how dysfunction and disease can be treated.
The eight distinguished speakers who participated in the 2021-2022 M.R. Bauer Colloquium Series are exploring how the invisible is essential, building an understanding of how changes at the level of ion channels, neuromodulators, and proteins can have major behavioral ramifications as far-ranging as an awareness of social rank and the initiation of long-term memory formation. Each speaker presented a summary of their work, which is preceded by a brief introduction set in italics, explaining in a more general framework the focus of the speaker’s work.
Jamie Maguire, PhD
Kenneth and JoAnn G. Wellner Professor
Department of Neuroscience
Tufts University School of Medicine
(September 14, 2021)
Erik Jorgensen, PhD
Distinguished Professor
School of Biological Sciences
University of Utah
Investigator
Howard Hughes Medical Institute
(November 30, 2021)
Scott Prescott, MD/PhD
Professor
Department of Physiology
University of Toronto
Senior Scientist, Neurosciences & Mental Health
Hospital for Sick Children
(12/7/2022)
Nancy Padilla Coreano, PhD
Assistant Professor
Department of Neuroscience
Principal Investigator
Evelyn F. & William McKnight Brain Institute
University of Florida
(3/15/2022)
Ishmail Abdus-Saboor, PhD
Assistant Professor
Department of Biological Sciences
Principal Investigator
Zuckerman Mind Brain Behavior Institute
Columbia University
(March 29, 2022)
Matthew Kayser, MD/PhD
Assistant Professor, Physician-of-Record
Department of Psychiatry
Perelman School of Medicine
University of Pennsylvania
(April 24, 2022)
Every year the M.R. Bauer Distinguished Lecturer program brings to campus two distinguished visitors who spend a full week at Brandeis. These weeklong visitors present talks to small and large groups, visit laboratories, and engage students, postdoctoral fellows, and faculty in informational and highly interactive conversations about shared areas of research interests. This program is a unique opportunity for our youngest scientists to meet and interact with prominent people in the field; few institutions have a program like this. The M.R. Bauer Foundation-supported weeklong visits are a highlight of each semester for the entire community.
Didier Y. R. Stainier, PhD ‘84
Director & Scientific Member
Department of Developmental Genetics
Max Planck Institute for Heart and Lung Research
(October 5, 2021)
Joseph S. Takahashi, PhD
Professor and Department Chair
Loyd B. Sands Distinguished Chair in Neuroscience
Department of Neuroscience
University of Texas Southwestern Medical Center
Investigator
Howard Hughes Medical Institute
(March 22, 2022)
The 2022 M.R. Bauer Summer Research Fellows are a special cohort. The have had to demonstrate exceptional growth and resilience due to the global pandemic, but they received invaluable mentorship from dedicated graduate students, post-doctoral researchers, and faculty members of the Division of Science. The M.R. Bauer Foundation's support of the Summer Science Fellowship program allowed our students to find confidence in a scientific setting and affirm their field of choice. Some undergraduate researchers are still scaling up their presence in labs due to the restrictions put into place to combat the spread of SARS-CoV-2. Others were in the lab for the first time due to these restrictions. Some of their work went to plan, while others learned that "non-significant" does not mean not invaluable. They developed enthusiasm, curiosity, and a willingness to stretch beyond their comfort zones.
The summer experience for this year’s M.R. Bauer Fellows culminated in SciFest XI on August 11, 2022, where the Fellows presented posters on their projects to a huge audience of Brandeis researchers as well as scientists from local biotech companies. The following pages contain abstracts for each Fellow’s poster, as well as personal statements describing how this opportunity supported their scientific growth and education. Each Fellow has also included a “Giving Back” statement. These statements describe the unique ways that this year’s M.R. Bauer Fellows gave back to their communities over the duration of their fellowships.
Angie Aguirre-Tobar
Garrity Lab
Department of Biology
Brandeis University
Emma Barash
Katz Lab
Department of Psychology
Brandeis University
Nicolas Buongiorno
Kern Lab
Department of Biochemistry
Brandeis University
Sabrina Casey
Sekuler Lab
Department of Psychology
Brandeis University
Shari Glass
Wingfield Lab
Department of Psychology
Brandeis University
Sam Greene
Van Hooser Lab
Department of Biology
Brandeis University
Daniel Grupin
Krauss Lab
Department of Chemistry
Brandeis University
Huilin Li
Gutchess Lab
Department of Psychology
Brandeis University
Ashley Moushegian
Snyder Lab
Department of Psychology
Brandeis University
Connor Zawacki
Miller Lab
Department of Biology
Brandeis University
As always, we thank the speakers who made visits this past year to share their research with us and to engage us in many hours of stimulating discussion and exchanges of ideas with Volen Center faculty, students, and postdoctoral fellows. We are also grateful to our visitors for forwarding to us their lecture summaries that form the basis of this report.
We especially acknowledge Kim MacKenzie, a past neuroscience PhD graduate, for her valuable contributions and editorial assistance in the preparation of this report.