Animations From Assembly Trajectories

Animations from selected dynamical simulation trajectories at different parameter values can be seen by clicking below. Please see Ref. [2] for a description of subunit geometries and definitions of parameters.

Successful assembly for subunit geometry B3. Note the frequency of unbinding events — only the most favorable assembly pathways lead to capsid growth.

Parameters: C0=0.11, εb=16.0, θm=0.5

Unsuccessful assembly for subunit geometry B3 — a kinetic trap:

Parameters: C0=0.11, εb=20.0, θm=1.5

Successful assembly for subunit geometry B4. Note the events in which different intermediates bind to each other in "Growth of nucleus".

Parameters: C0=0.11, εb=12.7, θm=0.5

Successful assembly for subunit geometry B5. Note that assembly occurs primarily through binding of monomers.

(Movies were made from typical simulation trajectories. The rendering was done by Stylus Visuals.)

More About Space-Time Analysis of Assembly Trajectories

Animations

Formation of Nucleus (Successful assembly for subunit geometry B3)

Formation of Nucleus (Successful assembly for subunit geometry B3)

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Growth of Nucleus (Successful assembly for subunit geometry B3)

Growth of Nucleus (Successful assembly for subunit geometry B3)

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Complete capsid

Complete Capsid (Successful assembly for subunit geometry B3)

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ormation of a nucleus (for subunit geometry B4)

Formation of a nucleus (for subunit geometry B4)

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Growth of a Nucleus (for subunit geometry B4)

Growth of a Nucleus (for subunit geometry B4)

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Penultimate Subunit (for subunit geometry B4)

Penultimate Subunit (for subunit geometry B4)

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Malformed Assembly  (for subunit geometry B3)

Malformed Assembly (for subunit geometry B3)

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