Contact Information
Jané Kondev
Abelson 301
(781) 736-2812
kondev@brandeis.edu
Jané Kondev
Professor of Physics
Ph.D., Cornell University, 1995
Jané Kondev is a theoretical physicist who works primarily on problems in molecular and cell biology. Research in the Kondev group is driven by quantitative experiments on single molecules and single cells, which are typically performed in biology labs the group collaborates with. The goal is to provide a mathematical framework that can explain the available quantitative data, and makes testable predictions that can guide new experiments. Members of the group are inspired by the new vistas that open up when life's processes are described in the language of theoretical physics, thus providing new insights about outstanding problems in biology.
Sample of Current Projects
- Transcriptional regulation of gene expression.
- Chromosome organization in bacteria and yeast.
- Tethering motifs in molecular biology.
- Effects of confinement and crowding on bi-molecular reaction rates.
Recent Ph.D. Students
Daniel Reeves (2010) "Diffusion Limited Reactions in Poorly Mixed Environments." Present Position: Postdoc, MIT, Department of Earth Atmospheric and Planetary Sciences, MA
Joshua Martin (2008) "Polymer Models of Chromatin" Present Position: Postdoctoral Associate, University of North Carolina
Ercan Kamber (2008) "Statistical Physics at Crowding and Confinement" Present Position: Vice President of HPC Engineering at RAID, MA
Ashok Prasad (2006) "Macromolecules in Flatland" Present Position: Assistant Professor, Chemical and Biological Engineering Department, Colorado State University, CO
Sample of Recent Publications
Schmit JD, Kamber E, and Kondev J. "Lattice Model of Diffusion-Limited Bimolecular Chemical Reactions in Confined Environments." Physical Review Letters 102. (2009): 218302.
Daniel Reeves, Tristan Ursell, Pierre Sens, Jane Kondev, and Rob Phillips. "Membrane mechanics as a probe of ion-channel gating mechanisms." Physical Review E 78. (2008): 041901.
Prasad, Ashok, Kondev, Jané and Stone, Howard. "Drift in supported membranes." Physics of Fluids 19. (2008): 113103.
Rob Phillips, Jané Kondev, and Julie Theriot. Physical Biology of the Cell. Garland Science, 2008.
Sanchez, Alvaro and Kondev, Jané. "Transcriptional control of noise in gene expression." Proceedings of the National Academy of Sciences 105. 13 (2008): 5081.