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Blender is somewhat easier to learn than Maya, but offers the same set of features. It also features an integrated physics engine (Bullet) and supports basic game engine scripting using Python.

Autodesk Maya 2015 logo
Autodesk Maya 2015

Maya is a professional 3d modeling and animation program. While it has a steep learning curve, the program has been used in many professional contexts, including game development and film. Maya is also very extendable; it has an internal scripting language that allows you to write your own plugins and use plugins designed by other users.

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Adobe Mudbox 2015

Mudbox is the perfect companion to Maya, offering a robust framework for 3d sculpting and painting.

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Adobe Animate

Adobe Animate (formerly Adobe Flash) is a multimedia authoring and 2-D computer animation program. It can be used to design vector graphics and animation.

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Cinema 4D

If you want to create advanced 3D graphics but need a helping hand to create them quickly and easily, then this is the tool for you. It offers easy integration with Adobe After Effects.