Jané Kondev

kondevProfessor of Physics

Degree

PhD, Cornell University, 1995

Research

Jané Kondev is a theoretical physicist who works primarily on problems in molecular and cell biology. Research in the Kondev group is driven by quantitative experiments on single molecules and single cells, which are typically performed in biology labs the group collaborates with. The goal is to provide a mathematical framework that can explain the available quantitative data, and makes testable predictions that can guide new experiments. Members of the group are inspired by the new vistas that open up when life's processes are described in the language of theoretical physics, thus providing new insights about outstanding problems in biology.

Group website   CV and list of publications (pdf)

Sample of Current Projects

Recent PhD Students

Sample of Recent Publications

"Operator sequence alters gene expression independently of transcription factor occupancy in bacteria." Garcia HG, Sanchez A, Boedicker JQ, Osborne ML, Gelles J, Kondev J, Phillips R (2012) Cell Reports, 2(1):150-161

"Dynamics of homology searching during gene conversion in Saccharomyces cerevisiae revealed by donor competition."  Coïc E, Martin J, Ryu T, Tay SY, Kondev J,Haber JE (2011) Genetics, 189(4):1225-33

"Mechanism of transcriptional repression at a bacterial promoter by analysis of single molecules." Sanchez A, Osborne ML, Friedman LJ, Kondev J, Gelles J (2011) EMBO J. 30(19):3940-6

"Regulation of biochemical reaction rates by flexible tethers." Reeves, D., Cheveralls, K., Kondev, J. (2011) Phys. Rev. E 84:021914

"Effect of Promoter Architecture on the Cell-to-Cell Variability in Gene Expression." Sanchez A, Garcia HG, Jones D, Phillips R, Kondev J (2011) PLoS Comput Biol 7(3): e1001100