Faculty & Research
Cellular organization and behavior in the Archaea domain of life
Regulation of protein phosphatases and the evolution of cellular signaling
Self-organization of living and active matter
Neural development and behavior
Single-molecule biochemistry and biophysics. Transcription and RNA processing. Cytoskeletal networks and regulation.
Expertise: Cytoskeletal mechanisms controlling cell morphogenesis.
Biochemistry of behavior
Repair of broken chromosomes and triggering of the DNA damage response.
Antimicrobial design; targeted protein degradation; TSC2 activators; enzyme structure-function studies
Molecular neurobiology and RNA metabolism
Mechanisms for control of mitochondrial protein activity, quality and lifespan
Physical biology of the cell
Chemical glycobiology and organic chemistry
Expertise: Genomics of brain development.
Genetics and molecular biology of bacteria and yeast
Gene expression in cellular stress responses
Physiological genomics of the mammalian neocortex
Molecular mechanisms of synaptic development.
Expertise: Molecular mechanisms of epigenetic inheritance; single molecule approaches to study chromatin associated factors in vitro and in cells.
Endosomal membrane traffic in neurons
Complex fluids and biological physics; programmable self-assembly of soft materials; colloidal interactions and phase transitions; DNA nanotechnology; self-organization of active matter; optical trapping and single-molecule science.
Expertise: Circadian rhythms, behavior and gene expression.
Neurogenetics of sensory behaviors
Mechanisms of protein folding in the cell
Expertise: Evolution, structure, and function of macromolecular complexes
Homeostasis and neural circuit plasticity and function