Our CMCB training faculty are from multiple departments and disciplines, and their research interests fall into five broad areas (see below). They are engaged in many close scientific collaborations and co-mentoring experiences, producing a highly interconnected network of cross-disciplinary relationships (see figure above).
DNA Replication and Repair
These groups use genetics, cell imaging, and quantitative modeling to elucidate DNA repair and replication mechanisms in yeast and bacteria.
These groups use in vitro reconstitution, single molecule imaging, genetics, genomics, and computational approaches to study mechanisms of transcription and translation, and how gene expression patterns control complex biological phenomena such as circadian rhythms and cortical function.
Cytoskeleton and cell motility
This group uses biochemistry, biophysics, single molecule imaging, live-cell imaging, and quantitative modeling to elucidate mechanisms of actin cytoskeleton remodeling, force generation, and motility in yeast and mammalian cells.
Cell shape and membrane compartmentalization
This group uses a range of model systems and approaches (including genetics, imaging and quantitative modeling) to study how cell architecture is specified.
Biology of pathogens
This group studies viral encapsulation and entry and eukaryotic parasites using chemical biology, quantitative modeling and in vitro reconstitution.
Bacteria and Archaea
This group focuses on the evolution, morphogenesis and physiology of bacteria and archaea using biochemistry, cellular imaging, genetics and computational phylogenetics.
This group uses biochemical and chemical biology approaches to study the regulation of protein production, folding and degradation.
This group uses genetics, biochemistry, physiology, and imaging to study how cells communicate with one another in complex tissues and how signals are transduced within cells.