About the Visualization Center

The center was founded in 1972 as the Laboratory of Structural Biology by Dr. Susan Lowey, Dr. Carolyn Cohen, and Dr. Don Caspar (who coined the term ‘structural biology’), joined shortly by Dr. David DeRosier. Other faculty members over the years include Dr. Hugh Huxley, Dr. Niko Grigorieff, and Dr. Daniela Nicastro (a fuller version of the history of the facility is available).

Services and Techniques

We offer wide variety of  transmisstion electron microscopy imaging methods, ranging from standard 2D TEM methods to high resolution 3D cryo-TEM. View a full list of available equipment.

Our expertise includes:

  • Sample Preparation: Negative staining; chemical fixation; plunge freezing; resin embedding; ultramicrotomy and serial sectioning; immuno-electron microscopy
  • TEM Imaging: 2D TEM imaging; TEM tomographic imaging; Single particle cryo and negative stain-EM imaging